{"id":16539,"date":"2025-12-05T12:48:58","date_gmt":"2025-12-05T11:48:58","guid":{"rendered":"https:\/\/www.gutblick.ch\/de\/?post_type=service&#038;p=16539"},"modified":"2025-12-08T17:00:21","modified_gmt":"2025-12-08T16:00:21","slug":"research-projects-english","status":"publish","type":"service","link":"https:\/\/www.gutblick.ch\/de\/leistungen\/research-projects-experts\/","title":{"rendered":"Current research projects \u2013 Information for experts"},"content":{"rendered":"<div itemscope itemtype=\"http:\/\/schema.org\/Article\" class=\"header-small-block container1200 mb120 mt120\"><div class=\"container\" > <div class=\"content\" > <div class=\"header-small-block-wrap\" > <div class=\"header-small-block__content\" > <h1 itemprop=\"name\" class=\"header-small-block__name semiBold h3\" > <span class=\"header-small-block__title h3\" > Current research projects \u2013<\/span><br>Information for experts<\/h1 > <p class=\"header-small-block__subtitle mt16\" > <\/p > <\/div > <div class=\"header-small-block__image\" > <img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1438\" src=\"https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Forschungsprojekte-scaled.webp\" class=\"img__small__header\" alt=\"\" srcset=\"https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Forschungsprojekte-scaled.webp 2560w, https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Forschungsprojekte-300x169.webp 300w, https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Forschungsprojekte-1024x575.webp 1024w, https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Forschungsprojekte-1536x863.webp 1536w, https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Forschungsprojekte-2048x1151.webp 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/div > <\/div > <\/div > <\/div > <\/div > \n\n<div class=\"title-content-block container1364 mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"mt24 mb24 max830 preloaded__content fade\"><p>Gutblick Research conducts clinical research projects in various areas of ophthalmology. The focus is on practical issues and high methodological quality. The research projects are carried out in cooperation with clinics, research institutions, and industry partners. Here you will find an overview of current studies, sorted by field of expertise.<\/p>\n<\/div><div class=\"mt24 mb24 max830 preloaded__content fade\"><p>Specialists who are interested in collaborating or including their patients in a study can find further information and contact details here.<\/p>\n<\/div><div class=\"mt24 mb24 max830 preloaded__content fade\"><p>The quality of Gutblick Research has been verified by external bodies. The following certifications have been awarded:<\/p>\n<\/div><div class=\"mt24 mb24 max830\"><ul><li class=\"mb24\">Good Clinical Practice (GCP)<p><\/p><\/li><li class=\"mb24\">Diversity &#038; Inclusion Research Conference (DIRC)<p><\/p><\/li><li class=\"mb24\">OptymEdge<p><\/p><\/li><li class=\"mb24\">IATA<p><\/p><\/li><\/ul><\/div><\/div><\/div><\/div>\n\n<div class=\"title-content-block container1364 mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"mt24 mb24 max830 preloaded__content fade\"><h2>Current research projects<\/h2>\n<\/div><div class=\"mt24 mb24 max830 preloaded__content fade\"><div style=\"display: flex; flex-direction: row; margin-bottom: 30px;\">\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-11396\" src=\"https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Gutblick_Icon-18_Forschung.svg\" alt=\"\" width=\"80\" height=\"80\" \/><\/p>\n<div class=\"quote-block__title\" style=\"margin-left: 30px;\"><strong style=\"color: var(--wp--preset--color--ow-primary-1);\">Research areas:<\/strong> Our research focuses on the macula, uveitis, retina, and state-of-the-art imaging diagnostics. Below you will find our current studies:<\/div>\n<\/div>\n<\/div><\/div><\/div><\/div>\n\n<div class=\"tabs-block container1150 mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"tabs-block-wrap\"><div class=\"tabs-block__nav\"><ul><li class=\"tabs-block__nav_item active\" tab-data=\"tab-1\">Macular and retinal diseases<\/li><li class=\"tabs-block__nav_item \" tab-data=\"tab-2\">Systemic diseases and ocular effects<\/li><\/ul><\/div><div class=\"tabs-block__content\"><div class=\"tabs-block__content_inner\"><div class=\"tabs-block__content_single active\" tab-data=\"tab-1\"><h4 class=\"mb24\">Spectrum<\/h4><p><html>\r\n<body><p>\r\n<strong> Description <\/strong><br>\r\n<ul>\r\n  <li>To describe the short and long term effectiveness of intravitreal aflibercept 8 mg in patients with na\u00efve or pretreated nAMD or DME in routine clinical practice in each of the participating countries and overall<\/li>\r\n  <li>To describe treatment pattern for the study eye in clinical practice in patients with na\u00efve or pretreated nAMD or DME treated with intravitreal aflibercept 8 mg in routine clinical practice in each of the participating countries and overall<\/li>\r\n  <li>To describe safety profile of intravitreal aflibercept 8 mg in patients with na\u00efve or pretreated nAMD or DME in routine clinical practice in each of the participating countries and overall<\/li><\/ul>\r\n<br>\r\n<strong>Goal of the study<\/strong><br>\r\nTo describe the effectiveness of intravitreal aflibercept 8 mg in patients with na\u00efve or pretreated nAMD or DME in routine clinical practice in each of the participating countries and overall.\r\n<br><br>\r\n<strong>Who can participate?<\/strong><br>\r\nRecruitment completed\r\n<br><br>\r\n<strong> Study locations <\/strong><br>\r\nBern, Wallisellen, Aarau, Wetzikon\r\n<br><br>\r\n<strong> BASEC Number <\/strong><br>\r\n2023-02079\r\n<br><br>\r\n<strong> Sponsor <\/strong><br>\r\nBayer<br>\r\n<\/p><\/body>\r\n<\/html><\/p><\/div><div class=\"tabs-block__content_single \" tab-data=\"tab-2\"><h4 class=\"mb24\">CAMBRIA-2<\/h4><p><html>\r\n<body><p>\r\nA Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next-Generation, Oral Selective Estrogen Receptor Degrader) Versus Standard Endocrine Therapy (Aromatase Inhibitor or Tamoxifen) as Adjuvant Treatment for Patients with ER+\/HER2- Early Breast Cancer and an Intermediate-High or High Risk of Recurrence Who Have Completed Definitive Locoregional Treatment and Have No Evidence of Disease<br><br>\r\n<strong> Description <\/strong><br>\r\n<ul>\r\n  <li>The study duration will be approximately 14 years.<\/li>\r\n  <li>The treatment duration for either arm in the study will be 7 years (84 months).<\/li>\r\n  <li>The visit frequency for study assessments during the study treatment phase will be every 3 months until Month 7 (ie, Screening, Month 1, Month 4) and every 6 months up to 84 months. Additional visits can occur per investigator\u2019s discretion and local SoC.<\/li>\r\n <li>The visit frequency during the follow-up phase will be every 12 months.<\/li><\/ul>\r\n<br><br>\r\n<strong>Goal of the study<\/strong><br>\r\nThe purpose of this study is to measure the safety and demonstrate the superiority of camizestrant \u00b1 abemaciclib as compared to standard ET \u00b1 abemaciclib of patients with ER+\/HER2- early breast cancer.\r\n<br><br>\r\n<strong>Who can participate?<\/strong><br>\r\nThe target population of interest in this study consists of patients with ER+\/HER2- early breast cancer, with an intermediate-high or high risk of disease recurrence who have completed definitive locoregional therapy and have no evidence of disease.<br><br>\r\nPatients are recruited exclusively by the Tumor und BrustZentrum St. Gallen. We do not directly enroll patients, but rather provide ophthalmologic examinations for the study.\r\n<br><br>\r\n<strong> Study locations <\/strong><br>\r\nTumor und Brustzentrum St. Gallen and the ophthalmological examination in St. Gallen<br>\r\n<br>\r\n<strong> BASEC Number <\/strong><br>\r\n2023-504031-41-00\r\n<br><br>\r\n<strong> Sponsor <\/strong><br>\r\nAstraZeneca<br>\r\n<\/p><\/body>\r\n<\/html><\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\n\n<div class=\"title-content-block container1364 hidden-block mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"image-content mt24 mb24\"><div class=\"image-content-wrap\"><h3 class=\"mb24\">Macular and retinal diseases<\/h3><p><\/p><\/div><div class=\"image-content-image\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"375\" src=\"https:\/\/www.gutblick.ch\/app\/uploads\/2022\/08\/Netzhautsprechstunde_Aarau-_blogbeitrag-1.jpg\" class=\"img__content\" alt=\"\" srcset=\"https:\/\/www.gutblick.ch\/app\/uploads\/2022\/08\/Netzhautsprechstunde_Aarau-_blogbeitrag-1.jpg 640w, https:\/\/www.gutblick.ch\/app\/uploads\/2022\/08\/Netzhautsprechstunde_Aarau-_blogbeitrag-1-300x176.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/div><\/div><\/div><\/div><\/div>\n\n<div class=\"text-box-block container1200 hidden-block mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"text-box-block-wrap\"><h4 class=\"text-box-block__title mb24\"><\/h4><div class=\"text-box-block__bulletpoints\"><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Study title<\/p><p class=\"text-box-block__bulletpoint-content\">Spectrum<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Goal of the study<\/p><p class=\"text-box-block__bulletpoint-content\"><strong>Primary objective<\/strong> <\/br>\r\nTo describe the effectiveness of intravitreal aflibercept 8 mg in patients with na\u00efve or pretreated nAMD or DME in routine clinical practice in each of the participating countries and overall.\r\n<\/br><\/br>\r\n<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Who can participate?<\/p><p class=\"text-box-block__bulletpoint-content\">Recruitment completed<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">More about the study<\/p><p class=\"text-box-block__bulletpoint-content\"><strong>Secondary objectives<\/strong> <\/br>\r\n<ul>\r\n  <li>To describe the short and long term effectiveness of intravitreal aflibercept 8 mg in patients with na\u00efve or pretreated nAMD or DME in routine clinical practice in each of the participating countries and overall  <\/li>\r\n  <li>To describe treatment pattern for the study eye in clinical practice in patients with na\u00efve or pretreated nAMD or DME treated with intravitreal aflibercept 8 mg in routine clinical practice in each of the participating countries and overall <\/li>\r\n  <li>To describe safety profile of intravitreal aflibercept 8 mg in patients with na\u00efve or pretreated nAMD or DME in routine clinical practice in each of the participating countries and overall<\/li>\r\n<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Study locations<\/p><p class=\"text-box-block__bulletpoint-content\">Wetzikon, Aarau, Bern, Wallisellen\r\n<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">BASEC Number<\/p><p class=\"text-box-block__bulletpoint-content\">2023-02079<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Sponsor<\/p><p class=\"text-box-block__bulletpoint-content\">Bayer<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\"><a href=\"https:\/\/www.gutblick.ch\/de\/leistungen\/research-projects-experts\/#contact\">     <img decoding=\"async\" src=\"https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Gutblick_Icon-1_Aerztekader.svg\"           alt=\"\"           style=\"width: 32px; height: 32px; vertical-align: middle; margin-right: 6px;\">     Contact details for referrers<\/a><\/p><p class=\"text-box-block__bulletpoint-content\"><\/p><\/div><\/div><\/div><\/div><\/div><\/div>\n\n<div class=\"title-content-block container1364 hidden-block mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"image-content mt24 mb24\"><div class=\"image-content-wrap\"><h3 class=\"mb24\">Systemic diseases and ocular effects<\/h3><p><\/p><\/div><div class=\"image-content-image\"><img loading=\"lazy\" decoding=\"async\" width=\"710\" height=\"413\" src=\"https:\/\/www.gutblick.ch\/app\/uploads\/2022\/08\/AdobeStock_216671660-1-1-1.jpeg\" class=\"img__content\" alt=\"\" srcset=\"https:\/\/www.gutblick.ch\/app\/uploads\/2022\/08\/AdobeStock_216671660-1-1-1.jpeg 710w, https:\/\/www.gutblick.ch\/app\/uploads\/2022\/08\/AdobeStock_216671660-1-1-1-300x175.jpeg 300w\" sizes=\"auto, (max-width: 710px) 100vw, 710px\" \/><\/div><\/div><\/div><\/div><\/div>\n\n<div class=\"text-box-block container1200 hidden-block mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"text-box-block-wrap\"><h4 class=\"text-box-block__title mb24\"><\/h4><div class=\"text-box-block__bulletpoints\"><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Study title<\/p><p class=\"text-box-block__bulletpoint-content\">CAMBRIA-2: A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next-Generation, Oral Selective Estrogen Receptor Degrader) Versus Standard Endocrine Therapy (Aromatase Inhibitor or Tamoxifen) as Adjuvant Treatment for Patients with ER+\/HER2- Early Breast Cancer and an Intermediate-High or High Risk of Recurrence Who Have Completed Definitive Locoregional Treatment and Have No Evidence of Disease\r\n<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Goal of the study<\/p><p class=\"text-box-block__bulletpoint-content\">The purpose of this study is to measure the safety and demonstrate the superiority of camizestrant \u00b1 abemaciclib as compared to standard ET \u00b1 abemaciclib of patients with ER+\/HER2- early breast cancer. \r\n<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Who can participate?<\/p><p class=\"text-box-block__bulletpoint-content\">The target population of interest in this study consists of patients with ER+\/HER2- early breast cancer, with an intermediate-high or high risk of disease recurrence who have completed definitive locoregional therapy and have no evidence of disease. <\/br>\r\nPatients are recruited exclusively by the <strong>Tumor und BrustZentrum St. Gallen.<\/strong> We do not directly enroll patients, but rather provide ophthalmologic examinations for the study.<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">More about the study<\/p><p class=\"text-box-block__bulletpoint-content\">Study details include:<\/br>\r\n<ul>\r\n  <li>The study duration will be approximately 14 years.<\/li>\r\n<li> The treatment duration for either arm in the study will be 7 years (84 months).<\/li>\r\n<li> The visit frequency for study assessments during the study treatment phase will be every 3 months until Month 7 (ie, Screening, Month 1, Month 4) and every 6 months up to 84 months. Additional visits can occur per investigator\u2019s discretion and local SoC.<\/li>\r\n<li> The visit frequency during the follow-up phase will be every 12 months.<\/li> \r\n<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Study locations<\/p><p class=\"text-box-block__bulletpoint-content\">Tumor und Brustzentrum St. Gallen and the ophthalmological examination in St. Gallen<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">BASEC Number<\/p><p class=\"text-box-block__bulletpoint-content\">2023-504031-41-00<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Sponsor<\/p><p class=\"text-box-block__bulletpoint-content\">AstraZeneca<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\"><a href=\"https:\/\/www.gutblick.ch\/de\/leistungen\/research-projects-experts#contact\">     <img decoding=\"async\" src=\"https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Gutblick_Icon-1_Aerztekader.svg\"           alt=\"\"           style=\"width: 32px; height: 32px; vertical-align: middle; margin-right: 6px;\">     Contact details for referrers<\/a><\/p><p class=\"text-box-block__bulletpoint-content\"><\/p><\/div><\/div><\/div><\/div><\/div><\/div>\n\n<div class=\"title-content-block container1364 mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"mt24 mb24 max830 preloaded__content fade\"><h2 id=\"contact\">Contact<\/h2>\n<\/div><div class=\"mt24 mb24 max830 preloaded__content fade\"><p>Would you like to nominate a patient for a clinical study at Gutblick Research or learn more about a possible collaboration? Please contact us.<\/p>\n<\/div><\/div><\/div><\/div>\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-3e41869c wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-ow-primary-5-color has-ow-primary-1-background-color has-text-color has-background has-medium-font-size has-custom-font-size wp-element-button\" href=\"mailto:gutblick-research@hin.ch\" style=\"border-radius:4px\" target=\"_blank\" rel=\"noreferrer noopener\">E-Mail<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-ow-primary-5-color has-ow-primary-1-background-color has-text-color has-background has-medium-font-size has-custom-font-size wp-element-button\" href=\"https:\/\/www.gutblick.ch\/app\/uploads\/2025\/10\/Zuweiserformular_A4_Forschung_5009264_10-25.pdf\" style=\"border-radius:4px\" target=\"_blank\" rel=\"noreferrer noopener\">Form<\/a><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"featured_media":17050,"menu_order":0,"template":"","service_category":[440],"class_list":["post-16539","service","type-service","status-publish","has-post-thumbnail","hentry","service_category-research-projects-and-publications"],"acf":{"sidebar_excerpt":"Informieren Sie sich als Expert:in \u00fcber aktuelle Studien und Forschungsprojekte von Gutblick Research.  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