{"id":17533,"date":"2025-12-05T13:11:01","date_gmt":"2025-12-05T12:11:01","guid":{"rendered":"https:\/\/www.gutblick.ch\/de\/?post_type=service&#038;p=17533"},"modified":"2025-12-09T08:52:09","modified_gmt":"2025-12-09T07:52:09","slug":"forschungsporjekte-informationen-fuer-expertinnen","status":"publish","type":"service","link":"https:\/\/www.gutblick.ch\/de\/leistungen\/forschungsprojektefuerexpertinnen\/","title":{"rendered":"Forschungsprojekte \u2013 Informationen f\u00fcr Expert:innen"},"content":{"rendered":"<div itemscope itemtype=\"http:\/\/schema.org\/Article\" class=\"header-small-block container1200 mb120 mt120\"><div class=\"container\" > <div class=\"content\" > <div class=\"header-small-block-wrap\" > <div class=\"header-small-block__content\" > <h1 itemprop=\"name\" class=\"header-small-block__name semiBold h3\" > <span class=\"header-small-block__title h3\" > Aktuelle Forschungsprojekte:<\/span><br>Informationen f\u00fcr Expert:innen<\/h1 > <p class=\"header-small-block__subtitle mt16\" > <\/p > <\/div > <div class=\"header-small-block__image\" > <img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1438\" src=\"https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Forschungsprojekte-scaled.webp\" class=\"img__small__header\" alt=\"\" srcset=\"https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Forschungsprojekte-scaled.webp 2560w, https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Forschungsprojekte-300x169.webp 300w, https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Forschungsprojekte-1024x575.webp 1024w, https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Forschungsprojekte-1536x863.webp 1536w, https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Forschungsprojekte-2048x1151.webp 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/div > <\/div > <\/div > <\/div > <\/div > \n\n<div class=\"title-content-block container1364 mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"mt24 mb24 max830 preloaded__content fade\"><p>Gutblick Research f\u00fchrt klinische Forschungsprojekte in verschiedenen Bereichen der Augenheilkunde durch. Der Schwerpunkt liegt auf praxisnahen Fragestellungen und hoher methodischer Qualit\u00e4t. Die Forschungsprojekte werden in Zusammenarbeit mit Kliniken, Forschungseinrichtungen und Industriepartnern durchgef\u00fchrt. Hier finden Sie eine \u00dcbersicht \u00fcber aktuelle Studien, sortiert nach Fachgebieten.<\/p>\n<\/div><div class=\"mt24 mb24 max830 preloaded__content fade\"><p>Fach\u00e4rzt:innen, die an einer Zusammenarbeit interessiert sind oder ihre Patient:innen in eine Studie einbeziehen m\u00f6chten, finden hier weitere Informationen und Kontaktdaten.<\/p>\n<\/div><div class=\"mt24 mb24 max830 preloaded__content fade\"><p>Die Qualit\u00e4t von Gutblick Research wurde von externen Stellen \u00fcberpr\u00fcft. Folgende Zertifizierungen wurden vergeben:<\/p>\n<\/div><div class=\"mt24 mb24 max830\"><ul><li class=\"mb24\">Good Clinical Practice (GCP)<p><\/p><\/li><li class=\"mb24\">Diversity &#038; Inclusion Research Conference (DIRC)<p><\/p><\/li><li class=\"mb24\">OptymEdge<p><\/p><\/li><li class=\"mb24\">IATA<p><\/p><\/li><\/ul><\/div><\/div><\/div><\/div>\n\n<div class=\"title-content-block container1364 mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"mt24 mb24 max830 preloaded__content fade\"><h2>Aktuelle Studien<\/h2>\n<\/div><div class=\"mt24 mb24 max830 preloaded__content fade\"><div style=\"display: flex; flex-direction: row; margin-bottom: 30px;\">\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-11396\" src=\"https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Gutblick_Icon-18_Forschung.svg\" alt=\"\" width=\"80\" height=\"80\" \/><\/p>\n<div class=\"quote-block__title\" style=\"margin-left: 30px;\"><strong style=\"color: var(--wp--preset--color--ow-primary-1);\">Forschungsbereiche:<\/strong> Unser Forschungsschwerpunkt liegt in den Bereichen Makula, Uveitis, Netzhaut und modernster bildgebender Diagnostik. Nachfolgend finden Sie unsere aktuellen Studien:<\/div>\n<\/div>\n<\/div><\/div><\/div><\/div>\n\n<div class=\"tabs-block container1150 mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"tabs-block-wrap\"><div class=\"tabs-block__nav\"><ul><li class=\"tabs-block__nav_item active\" tab-data=\"tab-1\">Makula- und Netzhauterkrankungen<\/li><li class=\"tabs-block__nav_item \" tab-data=\"tab-2\">Systemische Erkrankungen und okul\u00e4re Auswirkungen<\/li><\/ul><\/div><div class=\"tabs-block__content\"><div class=\"tabs-block__content_inner\"><div class=\"tabs-block__content_single active\" tab-data=\"tab-1\"><h4 class=\"mb24\">Spectrum<\/h4><p><html>\r\n<body><p>\r\n<strong> Beschrieb <\/strong><br>\r\n<ul><li>Beschreibung der kurz- und langfristigen Wirksamkeit von 8 mg intravitreal verabreichten Aflibercept bei Patient:innen mit unbehandelter oder vorbehandelter nAMD oder DME in der routinem\u00e4ssigen klinischen Versorgung in den einzelnen teilnehmenden L\u00e4ndern als auch insgesamt <\/li>\r\n  <li>Beschreibung des Behandlungsmusters f\u00fcr das Studienauge in der klinischen Praxis bei Patient:innen mit unbehandelter oder vorbehandelter nAMD oder DME, die mit intravitrealem Aflibercept 8 mg behandelt wurden \u2013 in den einzelnen teilnehmenden L\u00e4ndern als auch insgesamt <\/li>\r\n  <li>Beschreibung des Sicherheitsprofils von intravitrealem Aflibercept 8 mg bei Patient:innen mit unbehandelter oder vorbehandelter nAMD oder DME in der routinem\u00e4ssigen klinischen Versorgung  in den einzelnen teilnehmenden L\u00e4ndern als auch insgesamt <\/li><\/ul>\r\n<br><br>\r\n<strong>Ziel der Studie<\/strong><br>\r\n  Beschreibung der Wirksamkeit von 8 mg intravitrealem Aflibercept bei Patient:innen mit unbehandelter oder vorbehandelter nAMD oder DME im Rahmen der routinem\u00e4ssigen klinischen Versorgung in den einzelnen teilnehmenden L\u00e4ndern und insgesamt.\r\n<br><br>\r\n<strong>Wer kann teilnehmen?<\/strong><br>\r\nRekrutierung abgeschlossen\r\n<br><br>\r\n<strong> Standorte <\/strong><br>\r\nBern, Wallisellen, Aarau, Wetzikon\r\n<br><br>\r\n<strong> BASEC Nummer <\/strong><br>\r\n2023-02079\r\n<br><br>\r\n<strong> Sponsor <\/strong><br>\r\nBayer<br>\r\n<\/p><\/body>\r\n<\/html><\/p><\/div><div class=\"tabs-block__content_single \" tab-data=\"tab-2\"><h4 class=\"mb24\">CAMBRIA-2<\/h4><p><html>\r\n<body><p>\r\nA Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next-Generation, Oral Selective Estrogen Receptor Degrader) Versus Standard Endocrine Therapy (Aromatase Inhibitor or Tamoxifen) as Adjuvant Treatment for Patients with ER+\/HER2- Early Breast Cancer and an Intermediate-High or High Risk of Recurrence Who Have Completed Definitive Locoregional Treatment and Have No Evidence of Disease<br><br>\r\n<strong> Beschrieb <\/strong><br>\r\n<ul>\r\n  <li>Die Studiendauer betr\u00e4gt etwa 14 Jahre.<\/li>\r\n  <li>Die Behandlungsdauer f\u00fcr einen Studienarm umfasst 7 Jahre (84 Monate).<\/li>\r\n  <li>W\u00e4hrend der Behandlungsphase findet bis zum 7. Monat alle 3 Monate ein Termin statt (d.h. Screening im 1. Monat und 4. Monat) und danach alle 6 Monate bis zum 84. Monat. Zus\u00e4tzliche Termine k\u00f6nnen nach Ermessen der \u00c4rztin\/des Arztes und gem\u00e4ss den lokalen Standardbehandlungsprotokollen erfolgen.<\/li>\r\n <li>W\u00e4hrend der Nachbeobachtungsphase finden alle 12 Monate Termine statt.<\/li><\/ul>\r\n<br><br>\r\n<strong>Ziel der Studie<\/strong><br>\r\nDer Zweck dieser Studie ist es, die Sicherheit zu messen und die \u00dcberlegenheit von Camizestrant \u00b1 Abemaciclib im Vergleich zu Standard-ET \u00b1 Abemaciclib bei Patientinnen mit ER+\/HER2- Brustkrebs im Fr\u00fchstadium nachzuweisen.\r\n<br><br>\r\n<strong>Wer kann teilnehmen?<\/strong><br>\r\nDie Zielpopulation dieser Studie besteht aus Patientinnen mit ER+\/HER2- Brustkrebs im Fr\u00fchstadium, mit einem mittleren bis hohen Risiko f\u00fcr ein Wiederauftreten der Erkrankung, bei denen eine definitive lokoregionale Therapie abgeschlossen ist und keine Anzeichen einer Erkrankung vorliegen.<br><br>\r\nDie Patientinnen werden ausschliesslich vom Tumor- und Brustzentrum St. Gallen rekrutiert. Wir nehmen keine Patientinnen direkt in die Studie auf, sondern f\u00fchren lediglich die augen\u00e4rztlichen Untersuchungen f\u00fcr die Studie durch.\r\n<br><br>\r\n<strong> Standorte <\/strong><br>\r\nSt. Gallen \u2013 in Zusammenarbeit mit dem Tumor- und BrustZentrum St. Gallen<br>\r\n<br>\r\n<strong> BASEC Nummer <\/strong><br>\r\n2023-504031-41-00\r\n<br><br>\r\n<strong> Sponsor <\/strong><br>\r\nAstraZeneca<br>\r\n<\/p><\/body>\r\n<\/html><\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\n\n<div class=\"title-content-block container1364 hidden-block mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"image-content mt24 mb24\"><div class=\"image-content-wrap\"><h3 class=\"mb24\">Macular and retinal diseases<\/h3><p><\/p><\/div><div class=\"image-content-image\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"375\" src=\"https:\/\/www.gutblick.ch\/app\/uploads\/2022\/08\/Netzhautsprechstunde_Aarau-_blogbeitrag-1.jpg\" class=\"img__content\" alt=\"\" srcset=\"https:\/\/www.gutblick.ch\/app\/uploads\/2022\/08\/Netzhautsprechstunde_Aarau-_blogbeitrag-1.jpg 640w, https:\/\/www.gutblick.ch\/app\/uploads\/2022\/08\/Netzhautsprechstunde_Aarau-_blogbeitrag-1-300x176.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/div><\/div><\/div><\/div><\/div>\n\n<div class=\"text-box-block container1200 hidden-block mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"text-box-block-wrap\"><h4 class=\"text-box-block__title mb24\"><\/h4><div class=\"text-box-block__bulletpoints\"><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Study title<\/p><p class=\"text-box-block__bulletpoint-content\">Spectrum<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Goal of the study<\/p><p class=\"text-box-block__bulletpoint-content\"><strong>Primary objective<\/strong> <\/br>\r\nTo describe the effectiveness of intravitreal aflibercept 8 mg in patients with na\u00efve or pretreated nAMD or DME in routine clinical practice in each of the participating countries and overall.\r\n<\/br><\/br>\r\n<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Who can participate?<\/p><p class=\"text-box-block__bulletpoint-content\">Recruitment completed<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">More about the study<\/p><p class=\"text-box-block__bulletpoint-content\"><strong>Secondary objectives<\/strong> <\/br>\r\n<ul>\r\n  <li>To describe the short and long term effectiveness of intravitreal aflibercept 8 mg in patients with na\u00efve or pretreated nAMD or DME in routine clinical practice in each of the participating countries and overall  <\/li>\r\n  <li>To describe treatment pattern for the study eye in clinical practice in patients with na\u00efve or pretreated nAMD or DME treated with intravitreal aflibercept 8 mg in routine clinical practice in each of the participating countries and overall <\/li>\r\n  <li>To describe safety profile of intravitreal aflibercept 8 mg in patients with na\u00efve or pretreated nAMD or DME in routine clinical practice in each of the participating countries and overall<\/li>\r\n<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Study locations<\/p><p class=\"text-box-block__bulletpoint-content\">Wetzikon, Aarau, Bern, Wallisellen\r\n<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">BASEC Number<\/p><p class=\"text-box-block__bulletpoint-content\">2023-02079<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Sponsor<\/p><p class=\"text-box-block__bulletpoint-content\">Bayer<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\"><a href=\"https:\/\/www.gutblick.ch\/de\/leistungen\/research-projects-experts\/#contact\">     <img decoding=\"async\" src=\"https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Gutblick_Icon-1_Aerztekader.svg\"           alt=\"\"           style=\"width: 32px; height: 32px; vertical-align: middle; margin-right: 6px;\">     Contact details for referrers<\/a><\/p><p class=\"text-box-block__bulletpoint-content\"><\/p><\/div><\/div><\/div><\/div><\/div><\/div>\n\n<div class=\"title-content-block container1364 hidden-block mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"image-content mt24 mb24\"><div class=\"image-content-wrap\"><h3 class=\"mb24\">Systemic diseases and ocular effects<\/h3><p><\/p><\/div><div class=\"image-content-image\"><img loading=\"lazy\" decoding=\"async\" width=\"710\" height=\"413\" src=\"https:\/\/www.gutblick.ch\/app\/uploads\/2022\/08\/AdobeStock_216671660-1-1-1.jpeg\" class=\"img__content\" alt=\"\" srcset=\"https:\/\/www.gutblick.ch\/app\/uploads\/2022\/08\/AdobeStock_216671660-1-1-1.jpeg 710w, https:\/\/www.gutblick.ch\/app\/uploads\/2022\/08\/AdobeStock_216671660-1-1-1-300x175.jpeg 300w\" sizes=\"auto, (max-width: 710px) 100vw, 710px\" \/><\/div><\/div><\/div><\/div><\/div>\n\n<div class=\"text-box-block container1200 hidden-block mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"text-box-block-wrap\"><h4 class=\"text-box-block__title mb24\"><\/h4><div class=\"text-box-block__bulletpoints\"><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Study title<\/p><p class=\"text-box-block__bulletpoint-content\">CAMBRIA-2: A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next-Generation, Oral Selective Estrogen Receptor Degrader) Versus Standard Endocrine Therapy (Aromatase Inhibitor or Tamoxifen) as Adjuvant Treatment for Patients with ER+\/HER2- Early Breast Cancer and an Intermediate-High or High Risk of Recurrence Who Have Completed Definitive Locoregional Treatment and Have No Evidence of Disease\r\n<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Goal of the study<\/p><p class=\"text-box-block__bulletpoint-content\">The purpose of this study is to measure the safety and demonstrate the superiority of camizestrant \u00b1 abemaciclib as compared to standard ET \u00b1 abemaciclib of patients with ER+\/HER2- early breast cancer. \r\n<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Who can participate?<\/p><p class=\"text-box-block__bulletpoint-content\">The target population of interest in this study consists of patients with ER+\/HER2- early breast cancer, with an intermediate-high or high risk of disease recurrence who have completed definitive locoregional therapy and have no evidence of disease. <\/br>\r\nPatients are recruited exclusively by the <strong>Tumor und BrustZentrum St. Gallen.<\/strong> We do not directly enroll patients, but rather provide ophthalmologic examinations for the study.<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">More about the study<\/p><p class=\"text-box-block__bulletpoint-content\">Study details include:<\/br>\r\n<ul>\r\n  <li>The study duration will be approximately 14 years.<\/li>\r\n<li> The treatment duration for either arm in the study will be 7 years (84 months).<\/li>\r\n<li> The visit frequency for study assessments during the study treatment phase will be every 3 months until Month 7 (ie, Screening, Month 1, Month 4) and every 6 months up to 84 months. Additional visits can occur per investigator\u2019s discretion and local SoC.<\/li>\r\n<li> The visit frequency during the follow-up phase will be every 12 months.<\/li> \r\n<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Study locations<\/p><p class=\"text-box-block__bulletpoint-content\">Tumor und Brustzentrum St. Gallen and the ophthalmological examination in St. Gallen<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">BASEC Number<\/p><p class=\"text-box-block__bulletpoint-content\">2023-504031-41-00<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\">Sponsor<\/p><p class=\"text-box-block__bulletpoint-content\">AstraZeneca<\/p><\/div><div class=\"text-box-block__bulletpoint\"><p class=\"text-box-block__bulletpoint-title\"><a href=\"https:\/\/www.gutblick.ch\/de\/leistungen\/research-projects-experts#contact\">     <img decoding=\"async\" src=\"https:\/\/www.gutblick.ch\/app\/uploads\/2025\/08\/Gutblick_Icon-1_Aerztekader.svg\"           alt=\"\"           style=\"width: 32px; height: 32px; vertical-align: middle; margin-right: 6px;\">     Contact details for referrers<\/a><\/p><p class=\"text-box-block__bulletpoint-content\"><\/p><\/div><\/div><\/div><\/div><\/div><\/div>\n\n<div class=\"title-content-block container1364 mb120 mt120\"><div class=\"container\"><div class=\"content\"><div class=\"mt24 mb24 max830 preloaded__content fade\"><h2 id=\"contact\">Kontakt<\/h2>\n<\/div><div class=\"mt24 mb24 max830 preloaded__content fade\"><p>M\u00f6chten Sie eine Patientin oder einen Patienten f\u00fcr eine klinische Studie bei Gutblick Research vorschlagen oder mehr \u00fcber eine m\u00f6gliche Zusammenarbeit erfahren? 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