Current
research projects
Research is important so that we can better understand eye diseases and develop new treatments. At Gutblick’s ophthalmology practices, we regularly conduct research projects—for example, on retinal diseases, eye infections, or new medications. All research projects are conducted under medical supervision and in accordance with legal requirements.
Current research projects
- Macular and retinal diseases
- Systemic diseases and ocular effects
Spectrum
Description
An observational study program to evaluate the effectiveness of the drug aflibercept 8 mg in the treatment of diabetic macular edema (DME) and neovascular age-related macular degeneration (nAMD) under real-world conditions.
Goal of the study
This observational study aims to learn more about changes in visual acuity in patients with neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME) after starting treatment with the active ingredient aflibercept 8 mg.
Who can participate?
Recruitment completed
Locations
Bern, Wallisellen, Aarau, Wetzikon
CAMBRIA-2
Description
The international Phase III CAMBRIA-2 study is investigating the efficacy and safety of the new breast cancer drug camizestrant. For us, it is particularly relevant whether the drug causes any side effects in the eye.
Goal of the study
The aim of the CAMBRIA-2 study is to investigate whether camizestrant can reduce the relapse rate in patients with early ER+/HER2- breast cancer compared to the standard therapies currently available.
Who can participate?
Patients are recruited exclusively by the Tumor- und BrustZentrum Ostschweiz. We do not directly admit patients, but rather perform ophthalmological examinations as part of the study.
Locations
St. Gallen – in collaboration with the Tumor- und BrustZentrum Ostschweiz
Procedure
Patients are referred to us by the Tumor- und BrustZentrum Ostschweiz. The ophthalmological examinations take place in St. Gallen. We work closely with patients over several years and systematically record any possible side effects of the new medication on the eye.
Frequently asked questions
Many patients have questions about research in ophthalmology, such as what studies actually are or what consent means. We are happy to answer the most frequently asked general questions below.
Research is about gaining new insights in order to improve medicine. In ophthalmology, research is conducted to develop better diagnostic methods, more effective treatments, and new technologies. Research helps to provide patients with optimal care.
Better treatment options: One goal is to develop effective therapies for eye diseases. Early detection: Another goal is to detect diseases at an early stage in order to prevent damage. New technologies: A further goal is to improve diagnoses and treatments.
Academic research Academic research uses existing knowledge and data to develop practical solutions, such as new drugs or devices. Clinical research Clinical research tests drugs or therapies directly on patients. The aim is to verify their efficacy and safety.
In research, studies are used to test new treatment options. There are two types of studies: 1) Clinical studies (with patients) Clinical studies apply drugs or therapies directly to humans. The aim is to test the effectiveness of the therapy or to determine the dosage and safety of the drug. 2) Non-clinical studies (in the laboratory) Non-clinical studies test new active substances or devices on cells or animals. This is done to check safety before the active substances or devices are tested on humans. Non-clinical studies are not offered at Gutblick.
Patients must give their consent before participating in studies. There are two types of consent. Both ensure that patients participate in studies in an informed and voluntary manner: General declaration of consent (general consent) A general declaration of consent allows patient data to be used for studies. The data is anonymized or encrypted for further use. Example: A patient agrees that their data (e.g., measurements) may be used for research. Declaration of consent (for a specific study) A declaration of consent refers to a specific study. Patients receive all information about the procedure, objectives, and possible risks during the consultation. This information is always provided to the patient by a study physician, who also answers any questions.
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